Last look

A close-up look at the spliceosome, at last.

Major developments in cryo-electron microscopy in the past three or four years have led to the solution of a number of spliceosome structures at high resolution, e.g., the fully assembled but not yet active spliceosome (Bact), the spliceosome just after the first step of splicing (C), and the spliceosome activated for the second step (C*). Therefore 30 years of genetics and biochemistry of the ...

Bioturbation: a fresh look at Darwin's last idea.

Bioturbation refers to the biological reworking of soils and sediments, and its importance for soil processes and geomorphology was first realised by Charles Darwin, who devoted his last scientific book to the subject. Here, we review some new insights into the evolutionary and ecological role of bioturbation that would have probably amazed Darwin. In modern ecological theory, bioturbation is n...

Recombinant DNA: the last look before the leap.

The Marathon Encounter Group—Vision and Reality: Exhuming the Body for a Last Look

DOI 10.1037//1061-4087.54.3.186 Consulting Psychology Journal: Practice and Research, Vol. 54, No. 3, 186–198 186 world and change the course of human destiny! The millennium was just around the corner! And, since in 1967 I was in the process of completing one of the first, if not the first, doctoral dissertations studying marathon groups (Weigel, 1968), I felt like one of the pioneering Apollo...

Last Branching in Directed Last Passage Percolation

The 1+1 dimensional directed polymers in a Poissonean random environment is studied. For two polymers of maximal length with the same origin and distinct end points we establish that the point of last branching is governed by the exponent for the transversal fluctuations of a single polymer. We also investigate the density of branches.